Lezi zinto, ezibizwa nangokuthi ama-biomarker, zingalinganiswa kusetshenziswa ukuhlolwa kwegazi.Kodwa izinga eliphezulu lenye yalezi zomaka isimila akusho ukuthi unomdlavuza wesibeletho.
Odokotela abasebenzisi ukuhlolwa kwegazi komaka bethumba ukuze bahlole abantu abanengozi emaphakathi yomdlavuza wesibeletho.Kodwa ziwusizo ekuhloleni ukwelashwa komdlavuza wesibeletho kanye nokuhlola ukuqhubeka kwesifo noma ukuvela kabusha.
Kunezinhlobo eziningi ezahlukene zokuhlola izimpawu zesimila esibelethweni.Ukuhlolwa ngakunye kubheka uhlobo oluhlukile lwe-biomarker.
I-Cancer antigen 125 (CA-125) iyiphrotheni eyi-tumor marker esetshenziswa kakhulu yomdlavuza wesibeletho.Ngokusho kwe-Ovarian Cancer Research Consortium, ngaphezu kwamaphesenti angu-80 abesifazane abanomdlavuza we-ovarian ophakeme kanye namaphesenti angu-50 abesifazane abanomdlavuza we-ovarian wesigaba sokuqala baye baphakamisa amazinga egazi e-CA-125.
Ngokusho kweNational Cancer Institute (NCI), ububanzi obujwayelekile bungamayunithi angu-0 kuye kwangama-35 ngemililitha ngayinye.Amazinga angaphezu kwama-35 angase abonise ukuba khona kwama-ovarian tumors.
I-Human epididymal protein 4 (HE4) ingenye umaka wesimila.Kuvame ukuvezwa ngokweqile kumaseli omdlavuza we-ovarian we-epithelial, okungamaseli ongqimba olungaphandle lwe-ovary.
Amanani amancane e-HE4 nawo angatholakala egazini labantu abangenawo umdlavuza wesibeletho.Lokhu kuhlola kungasetshenziswa ngokuhambisana nokuhlolwa kwe-CA-125.
I-Cancer antigen 19-9 (CA19-9) iphakeme kwezinye izinhlobo zomdlavuza, kuhlanganise nomdlavuza we-pancreatic.Kancane kancane, ihlotshaniswa nomdlavuza wesibeletho.Ingase futhi ibonise izimila ze-benign ovarian noma ezinye izimo ezinhle.
Ungakwazi futhi ukuhlala unempilo futhi ube nenani elincane le-CA19-9 egazini lakho.Lokhu kuhlola akuvamile ukusetshenziselwa ukuthola umdlavuza wesibeletho.
Embikweni ka-2017, odokotela babhala ukuthi ukusetshenziswa kwalesi simila sokubikezela umdlavuza we-ovarian kufanele kugwenywe ngoba kungase kubangele ukukhathazeka kunokuxilongwa okuqondile.
Ezinye izinhlobo zomdlavuza wesisu nabesifazane zihlotshaniswa namazinga aphezulu e-antigen 72-4 (CA72-4) yomdlavuza.Kodwa akulona ithuluzi eliphumelelayo lokuxilonga umdlavuza wesibeletho.
Ezinye izimpawu zesimila zingabonisa ukuba khona komdlavuza we-germ cell ovarian.Umdlavuza we-ovarian wegciwane kwenzeka kumaseli egciwane, okungamaseli aba iqanda.Lawa mamaki afaka:
Izimpawu zesimila zizodwa azikuqinisekisi ukutholakala komdlavuza wesibeletho.Odokotela basebenzisa izimpawu zomdlavuza wesibeletho nezinye izivivinyo ukusiza ukuxilonga.
I-CA-125 iwuphawu lwesimila olusetshenziswa kakhulu kumdlavuza wesibeletho.Kodwa uma amazinga akho e-CA-125 ejwayelekile, udokotela wakho angase ahlole i-HE4 noma i-CA19-9.
Uma unezimpawu noma izimpawu zomdlavuza wesibeletho, udokotela wakho angase aqale ngokuhlolwa ngokomzimba.Umlando wakho wezempilo womuntu siqu kanye nomndeni nawo udlala indima.Ngokusekelwe kulokhu okutholakele, izinyathelo ezilandelayo zingabandakanya:
Uma umdlavuza wesibeletho usutholakele, izimpawu zesimila zingasiza ekwelapheni.Lezi zivivinyo zingasungula amazinga ayisisekelo kwezinye izimpawu zesimila.Ukuhlola okuvamile kungaveza ukuthi amazinga omaka isimila ayakhuphuka noma ehla.Lokhu kubonisa ukuthi ingabe ukwelashwa kuyasebenza noma uma umdlavuza uqhubeka.
Lokhu kuhlola kungasiza futhi ukulawula ukuphindeka, okusho ukuthi umdlavuza ubuya isikhathi esingakanani ngemva kokwelashwa.
Ukuhlolwa kokuhlola kusetshenziselwa ukuthola umdlavuza kubantu abangenazo izimpawu.Azikho izivivinyo ezitholakalayo zomaka isimila ezinokwethenjelwa ngokwanele ukuze zihlole abantu abasengozini elinganiselwe yomdlavuza wesibeletho.
Isibonelo, akuzona zonke iziguli ezinomdlavuza we-ovarian eziye zaphakamisa amazinga e-CA-125.Ngokusho kwe-Ovarian Cancer Research Consortium, ukuhlolwa kwegazi kwe-CA-125 kungaphuthelwa yisigamu samacala.Kunezimbangela ezimbalwa ezingezinhle zamazinga aphezulu e-CA-125.
Inhlanganisela ye-CA-125 ne-HE4 ingase ibe usizo ekuhloleni amaqembu omdlavuza wesibeletho osengozini enkulu.Kodwa lezi zivivinyo aziwuhlonzi ngokuqondile umdlavuza wesibeletho.
I-United States Preventive Services Task Force (USPSTF) ayikuncomi okwamanje ukuhlolwa okujwayelekile nganoma iyiphi indlela yabantu abangenazimpawu noma abasengozini enkulu yomdlavuza wesibeletho.Abacwaningi bafuna izindlela ezinembe kakhulu zokuthola lesi simo.
Izimpawu zesimila zomdlavuza we-ovarian zingasiza ekuhloleni abantu abasengozini enkulu yomdlavuza we-ovarian.Kodwa ukuhlolwa kwegazi kukodwa akwanele ukwenza ukuxilongwa.
Izimpawu zesimila zomdlavuza we-ovarian zingasiza ekuhloleni ukusebenza kokwelashwa futhi zibone ukuqhubeka kwesifo.
Ngokwesibuyekezo sango-2019, ngaphezu kwama-70% omdlavuza wesibeletho asesigabeni esithuthukile ngesikhathi sokuxilongwa.Ucwaningo lusaqhubeka, kodwa okwamanje akukho ukuhlolwa okuthembekile komdlavuza wesibeletho.
Yingakho kubaluleke kakhulu ukuqaphela izimpawu eziyisixwayiso futhi uzibike kudokotela wakho.Uma ucabanga ukuthi usengozini enkulu yokuba nomdlavuza wesibeletho, buza udokotela wakho ukuthi yiziphi izivivinyo ezingakusiza futhi uma zikhona izindlela zokwehlisa ingozi yakho.
Umdlavuza wesibeletho unezimpawu eziyisixwayiso, kodwa izimpawu zokuqala azicacile futhi kulula ukuziba.Funda ngezimpawu nokwelashwa komdlavuza wesibeletho.
Umdlavuza wesibeletho uvame kakhulu kwabesifazane asebekhulile.Iminyaka emaphakathi ekuxilongweni komdlavuza wesibeletho yayiyiminyaka engama-63.Umdlavuza we-ovarian wesigaba sokuqala awuvamile ukuvela nezimpawu…
Uma kutholakale ukuthi unomdlavuza we-ovarian, kungokwemvelo ukungabaza ukubikezela kwakho.Funda mayelana namazinga okusinda, umbono nokunye.
Okwamanje asikazi ukuthi yini ebangela umdlavuza wesibeletho.Kepha abacwaningi bahlonze izinto eziyingozi ezikhulisa amathuba okuba nomdlavuza we-ovarian…
Umdlavuza wesibeletho wuhlobo lwe-10 oluvame kakhulu lomdlavuza kwabesifazane baseMelika.Lo mdlavuza kungaba nzima ukuwubona, kodwa kwabanye...
Umdlavuza we-ovarian mucinous wuhlobo lomdlavuza oluyivelakancane olubangela isimila esikhulu kakhulu esiswini.Funda kabanzi ngalo mdlavuza, okuhlanganisa izimpawu nokwelashwa.
Ukuphuza utshwala ngokwakho akuyona ingozi enkulu yomdlavuza wesibeletho, kodwa ukuphuza utshwala kungabhebhethekisa ezinye izici eziyingozi.Kuwukwazi.
Funda kabanzi mayelana nocwaningo lwakamuva lwe-immunotherapy yomdlavuza we-ovarian, okuhlanganisa ukulinganiselwa kwawo kanye nokusetshenziswa kokwelashwa okuhlangene.
Umdlavuza we-ovarian wezinga eliphansi ubaphatha kabi abantu abasha futhi ungase ungazweli ekwelashweni.Sibheka izimpawu, ukuxilongwa kanye nokwelashwa…
Ukwelashwa kwamanje komdlavuza wesibeletho kungawuhlehlisa umdlavuza wesibeletho futhi kuwulethe ekuxolelweni.Kodwa-ke, ukunakekelwa okusekelayo kungadingeka ukuvimbela…
Isikhathi sokuthumela: Sep-23-2022
