Isingeniso:
Abahlaziyi be-Chemiluminescence immunoassay babambe iqhaza elibalulekile emkhakheni wokuxilongwa komtholampilo, beguqula ukutholwa kanye nomthamo wama-biomarker.Kulesi sihloko, sihlolisisa umlando walaba bahlaziyi, intuthuko yabo kwezobuchwepheshe, nomthelela abaye baba nawo ekuxilongweni kwezokwelapha.
1. Ukuvela Kwe-Chemiluminescence Immunoassays:
Umqondo we-chemiluminescence immunoassays wethulwa maphakathi nawo-1960 njengendlela engase ibe enye kuma-enzyme immunoassays avamile.Ucwaningo lokuqala lwalugxile ekusebenziseni ukusabela okusekelwe ku-luminol ukuze kukhiqizwe amasiginali okukhanya ekubopheni ama-antigen namasosha omzimba.Kodwa-ke, ukulinganiselwa kokuzwela kanye nokucaciswa kwawo kwavimbela ukwamukelwa kwabo okusabalele.
2. Intuthuko Yezobuchwepheshe:
Ngokuhamba kweminyaka, intuthuko ebalulekile yezobuchwepheshe iqhubekisele phambili ukuthuthukiswa kwabahlaziyi be-chemiluminescence immunoassay.Amalebula e-chemiluminescent athuthukisiwe, njenge-acridinium esters nomaka we-alkaline phosphatase, athuthukise ukuzwela nokuzinza kwezivivinyo.Ukwengeza, ukuvela kwamapulatifomu esigaba esiqinile, okuhlanganisa ama-microparticles kanye nobuhlalu kazibuthe, kusize ukuthwebula okuphumelelayo nokuhlukaniswa kwama-analytes.
3. Ukutholwa Kokuxilonga:
Ukwamukelwa ngempumelelo kwe-chemiluminescence immunoassay analyzers kumalabhorethri okuxilonga kwenzeka ngasekupheleni kwawo-1980 nasekuqaleni kwawo-1990.Laba bahlaziyi banikeze izinzuzo ezimbalwa, okuhlanganisa izikhathi zokushintsha ngokushesha, amandla okuthola ukuhlaziya okubanzi, nokunemba okuhle kakhulu.Ngenxa yalokho, baba nesandla ekuxilongeni nasekuqaphelweni kwezimo ezihlukahlukene zezokwelapha, kusukela ezifweni ezithathelwanayo kuya ekuphazamisekeni kwama-hormone kanye nokuphazamiseka kwe-autoimmune.
4. Ukuhlanganiswa kwe-Automation:
Eminyakeni yamuva nje, ukuhlanganiswa kokuzenzakalela kubahlaziyi be-chemiluminescence immunoassay kuye kwahlehlisa futhi ukuhlolwa kokuxilonga.Ukuphathwa kwesampula okuzenzakalelayo, ukukhishwa kwe-reagent, kanye nokutolika kwemiphumela kuye kwanciphisa kakhulu umsebenzi wezandla namaphutha angaba khona.Ngaphezu kwalokho, amarobhothi nama-algorithms esoftware athuthukile anika amandla ukuhlolwa okuphezulu, okuvumela amalabhorethri ukuthi acubungule inani elikhulu lamasampula ngendlela efanele.
5. Amathemba Ekusasa:
Ikusasa labahlaziyi be-chemiluminescence immunoassay lithembisa intuthuko eqhubekayo.Ucwaningo oluqhubekayo lugxile ekuthuthukiseni amakhono okuphindaphinda, ukwenza kahle ukuhlola, kanye nokuthuthukisa izixhumanisi ezisebenziseka kalula.Ngaphezu kwalokho, ukuhlanganiswa kobuhlakani bokwenziwa kanye nama-algorithms okufunda komshini kunamandla amakhulu okuhumusha idatha yokuhlola eyinkimbinkimbi nokukhiqiza imibiko yokuxilonga enembayo.
Isiphetho:
Ukuthuthukiswa kwezihlaziyi ze-chemiluminescence immunoassay kuphawula ingqopha-mlando ebalulekile emlandweni wokuxilongwa kwezokwelapha.Kusukela ekuqaleni kwabo okuphansi kuya kubuchwepheshe babo besimanjemanje, laba bahlaziyi baye bashintsha ukutholwa kwe-biomarker futhi bavula indlela yokuhlola ukuxilonga okunembe kakhudlwana nokusebenza kahle.Njengoba ubuchwepheshe buqhubeka nokuvela, abahlaziyi be-chemiluminescence immunoassay ngokungangabazeki bazodlala indima ebalulekile ekuthuthukiseni ukunakekelwa kwesiguli kanye nokuqhubekisela phambili umkhakha wokuxilongwa komtholampilo.
Isikhathi sokuthumela: Jun-21-2023
